Buy Oxycodone Powder – High-Purity Reference Standard for Analytical & Forensic Research | Research Stimulants

Research Stimulants provides pharmaceutical-grade oxycodone powder, a semisynthetic opioid optimized for advanced laboratory and analytical research. This fine white hydrochloride powder offers exceptional purity and solubility, ideal for receptor binding studies, pharmacokinetic modeling, and forensic analysis. Strictly for licensed scientific use, it supports precise investigations into opioid pharmacology.

Key Features

• Pharma-Grade Purity: ≥99% purity verified by HPLC, NMR, and USP standards.

• Fine Powder Form: Micronized for rapid dissolution in aqueous buffers and organic solvents.

• Scalable Packaging: 100mg to 10g+ with inert atmosphere sealing for research labs.

• Regulatory Documentation: CoA, SDS, and reference spectra included.

Oxycodone powder serves as a gold-standard reference for opioid research applications.

What is oxycodone?

Oxycodone hydrochloride (C18H21NO4·HCl, MW 351.83) is a semisynthetic opioid agonist derived from thebaine, featuring mu, kappa, and delta receptor affinity. The white crystalline powder is readily soluble in water, sparingly in ethanol, and insoluble in ether, with a pH of 3.0-4.0 in solution. Melting point approximately 255°C (dec).​

Synthesis involves thebaine oxidation followed by reduction and N-methylation. Chiral at C14, the 14-hydroxy configuration drives potency. UV max 230 nm and IR carbonyl at 1720 cm⁻¹ characterize the structure.

Research Applications

Oxycodone powder enables critical studies at Research Stimulants:

• Receptor Binding: Mu-opioid Ki ~20 nM in displacement assays.

• Pharmacokinetic Profiling: CYP3A4/2D6 metabolism to noroxycodone/oxymorphone.

• Abuse Deterrent Testing: Matrix extraction resistance evaluation.

• Forensic Toxicology: LC-MS/MS calibration standards.

Human PK shows Tmax 1-2 hours IR, bioavailability ~60-87% with food effect minimal.​

Ideal for controlled substance schedule II research protocols.

Why Choose Research Stimulants?

Research Stimulants supplies DEA-compliant oxycodone powder with chain-of-custody documentation and third-party ISO testing. Desiccated amber vials maintain stability per USP <1174> powder standards. Licensed researchers trust our compliance expertise, rapid fulfillment, and institutional pricing.

Powder form enables microgram-level dosing for receptor studies unattainable with tablets.

Usage Guidelines for Research

Laboratory protocols:

• Storage: 2-8°C desiccator; 5+ year stability under nitrogen.

• Solubility: 50 mg/mL water, 100 mg/mL methanol; pH adjust for stability.

• Analytical Prep: Dissolve in mobile phase 0.1% formic acid/ACN for LC-MS.

• Safety: Schedule II controlled; Category 2 exposure control (30 µg/m³ OEL).​

SDS specifies H302/H336 hazards, P261 ventilation, and spill neutralization with bisulfite.

Effects Profile in Research Models

Oxycodone powder demonstrates:

• Analgesic Activity: Potent mu-agonism with rapid onset, euphoria via VTA.

• Pharmacodynamics: Respiratory depression H=Warning level; miosis, sedation.

• Tolerance Dynamics: Escalation within days; noradrenergic withdrawal.

• Abuse Metrics: High reward liability, nasal bioavailability ~76%.​

Extended-release matrix research shows gel formation deterring extraction.

Customer Research Insights

Institutional researchers endorse:

• “USP-grade oxycodone powder perfected our mu-receptor assays.” – Dr. P., Pain Research Lab

• “Compliance docs flawless for our forensic validation suite.” – Prof. Q., Toxicology Institute

Feedback validates Research Stimulants’ opioid standard leadership.

Frequently Asked Questions

Purity certification?
≥99% USP/NF with full monograph compliance.​

Regulatory handling?
Schedule II; requires DEA licensing for possession.​

Shipping compliance?
Secure, documented carriers; institutional verification required.

Analytical quantities?
Yes, 50mg reference standards available.

Advance opioid research with oxycodone powder from Research Stimulants. Licensed lab orders fulfilled with full compliance.