Buy Methamphetamine Powder/Crystal | Research Stimulants

Research Stimulants supplies pharmaceutical-grade methamphetamine hydrochloride powder, the definitive reference standard for advanced neuropharmacology and stimulant research. This fine white crystalline powder delivers exceptional purity and solubility, ideal for dopamine transporter studies, addiction modeling, and forensic toxicology applications. Exclusively for licensed laboratory use under DEA Schedule II regulations, it ensures precise analytical and experimental reproducibility.

Key Features

• Analytical Reference Purity: ≥99.5% purity confirmed by chiral HPLC, GC-MS, and NMR.

• Ultra-Fine Crystal Powder: Optimized for quantitative dissolution and microgram precision.

• Institutional Quantities: 50mg reference standards to gram-scale research batches.

• Regulatory Compliance Package: DEA-formatted CoA, chain-of-custody docs, SDS.

Methamphetamine HCl serves as the gold standard for amphetamine-class research worldwide.

What is Methamphetamine?

Methamphetamine hydrochloride (d-methamphetamine HCl; CAS 51-57-0) features an N-methyl substitution on the amphetamine backbone with alpha-methyl chirality favoring the S-(+)-enantiomer. Formula C10H15N·HCl, molecular weight 185.70 g/mol. White odorless crystals melt at 170-175°C, highly water-soluble (1g/mL), with pKa 9.87 and logP 2.07. Characteristic UV λmax 251 nm, 13C-NMR confirms d-isomer >98% ee.

Synthesis via reductive amination of phenylacetone (P2P) with methylamine yields racemic, resolved chromatographically to d-form for research potency. Distinguishes from l-methamphetamine by 5-10x DAT affinity.

Research Applications

Methamphetamine HCl drives essential Schedule II investigations at Research Stimulants:

• Neurotransmitter Dynamics: Potent DAT/NET/VMAT2 reverse transport mechanism.

• Addiction Neuroscience: Ventral striatal dopamine surge, cue-reactivity paradigms.

• Neurotoxicity Modeling: DA terminal degeneration via oxidative stress cascades.

• Pharmacokinetic Standards: CYP2D6 demethylation to amphetamine calibration.

Rodent models demonstrate locomotor sensitization peaks day 5-7, microdialysis confirms striatal DA 1000% baseline elevation.

Establishes methamphetamine as prototype psychostimulant for addiction research.

Why Choose Research Stimulants?

Research Stimulants provides DEA-registered methamphetamine HCl with NIST-traceable purity certification and tamper-evident institutional packaging. Chiral resolution ensures >99% d-isomer critical for receptor studies. Licensed researchers specify our batch-matched lots, expedited compliance review, and Schedule II transfer protocols.

d-Methamphetamine powder eliminates racemic impurities confounding transporter assays.

Usage Guidelines for Research

Strict regulatory protocols:

• Storage: -20°C desiccator under nitrogen; 5+ year USP stability.

• Analytical Prep: Dissolve in 0.1N HCl or ammonium formate for LC-MS/MS.

• Animal Administration: IP/SC; Tmax 15-30 min, behavioral effects 6-12 hrs.

• Containment: DEA Schedule II vault; Category 1a airborne exposure controls.

SDS classifies H300+H370 hazards, requires P260/P280/P308+P313 response sequence.

Effects Profile in Research Models

Methamphetamine HCl pharmacological signature:

• Core Mechanism: VMAT2 depletion → cytoplasmic DA surge → DAT reversal → euphoria/reward.

• Neuropharmacology: 5HT/NE co-release, sigma receptor agonism, locomotor sensitization.

• Duration Profile: Acute 8-12 hrs, accumulation with q4h redosing common in models.

• Chronic Adaptation: DAT downregulation, gliosis, striatal DA transporter loss 20-50%.

Distinguishes from cocaine by intracellular vesicle mobilization and extended t½ ideal for tolerance studies.

Customer Research Insights

Institutional investigators validate:

• “NIST-traceable d-methamphetamine HCl perfected our addiction neuroimaging suite.” – Dr. X., NIDA-funded Lab

• “Schedule II compliance flawless; batch purity exceeded pharmacopeia specs.” – Prof. Y., Forensic Toxicology Center

DEA-licensed feedback confirms analytical supremacy.

Frequently Asked Questions

Chiral purity specification?

99% d-isomer ee with enantiomeric excess certificate.

Schedule II transfer requirements?
DEA Form 222 mandatory; institutional registration verification.

Analytical reference suitability?
USP/NIST compliant for LC-MS/GC-MS method validation.

Authorized recipient verification?
Pre-shipment registrant confirmation required.

Conduct definitive amphetamine research with methamphetamine hydrochloride from Research Stimulants. DEA-compliant excellence for licensed institutions.