Heroin Powder For Sale
$180.00 – $4,500.00Price range: $180.00 through $4,500.00
Buy Heroin Powder Online—High-Purity Reference Standard for Analytical & Forensic Research | Research Stimulants
Research Stimulants provides analytical-grade heroin powder (diacetylmorphine hydrochloride), the definitive reference standard for sophisticated opioid pharmacology and neurochemical investigations. This fine white crystalline powder offers exceptional purity and solubility, ideal for mu-opioid receptor binding assays, pharmacokinetic modeling, and forensic toxicology analysis. Strictly for licensed DEA Schedule I laboratory research, ensuring precise experimental reproducibility.
Key Features
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Reference Standard Purity: ≥99% purity verified by chiral HPLC, LC-MS, and NMR spectroscopy.
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Ultra-Fine Powder Morphology: Optimized for quantitative dissolution in aqueous and organic media.
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Institutional Scale: 50mg analytical references to gram-scale research batches.
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Compliance Documentation: DEA Schedule I CoA, impurity profiles, chain-of-custody records.
Heroin powder serves as the gold standard for opiate alkaloid research applications.
What is Heroin?
Heroin hydrochloride (diacetylmorphine HCl; CAS 1502-95-0) is the diacetyl ester of morphine, featuring 3,6-O-diacetylation on the morphine scaffold. Formula C21H23NO5·HCl, molecular weight 369.87 g/mol. White odorless powder melts at 243°C (dec), exhibits high water solubility (33 mg/mL), pKa 8.15, and characteristic UV λmax 280 nm. Rapid hydrolysis by plasma esterases regenerates active 6-monoacetylmorphine (6-MAM) and morphine.
Synthesis acetylates morphine base with acetic anhydride, followed by HCl salting and recrystallization. Distinguishes from morphine by 2-4x potency and faster CNS penetration due to lipophilicity (logP 1.85 vs 0.9).
Research Applications
Heroin powder enables critical Schedule I opioid studies at Research Stimulants:
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Receptor Pharmacodynamics: Mu-opioid Ki 1-10 nM, rapid G-protein signaling cascade.
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Metabolic Profiling: Esterase-mediated conversion 6-MAM > morphine urinary biomarkers.
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Neuroimaging Standards: PET ligand displacement for mu-receptor occupancy mapping.
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Abuse Liability Testing: Self-administration thresholds, conditioned reinforcement models.
Rodent studies demonstrate heroin microinjections produce dose-dependent analgesia 10x more potent than morphine mg:mg.
| Research Area | Key Pharmacological Metrics | Model Dosage (mg/kg IV) |
|---|---|---|
| Mu-Receptor Ki | 1-10 nM | N/A |
| Analgesia ED50 | 0.1-0.5 mg/kg | 0.1-1 |
| Brain Penetration | Tbrain 2-5 min | N/A |
| 6-MAM Formation | Peak 15 min plasma | 0.5-2 |
Establishes heroin as prototype lipophilic opioid for blood-brain barrier research.
Why Choose Research Stimulants?
Research Stimulants supplies DEA-registered heroin powder with USP-traceable purity certification and institutional tamper-proof packaging. Multi-stage recrystallization eliminates 6-MAM/morphine impurities <0.1%, critical for metabolic profiling. Schedule I researchers specify our batch traceability, expedited compliance verification, and controlled substance transfer protocols.
Heroin powder eliminates formulation variables confounding pure receptor studies versus pharmaceutical extracts.
Usage Guidelines for Research
Regulatory laboratory protocols:
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Storage: -20°C nitrogen desiccator; 3+ year analytical stability.
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Analytical Preparation: Dissolve 0.1% formic acid/ACN for LC-MS/MS heroin/6-MAM/morphine separation.
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In Vitro Assays: 1-100 nM working concentrations in binding/functional assays.
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Containment: Schedule I secure vault; SCBA required for aerosol generation studies.
SDS classifies H300 lethal toxicity, mandates P260/P284/P310 emergency response.
Effects Profile in Research Models
Heroin powder pharmacological characteristics:
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Rapid Mu-Agonism: Lipophilic diffusion → VTA inhibition → striatal DA surge within 60 seconds IV.
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Prodrug Kinetics: 6-MAM intermediate 3x more potent than morphine at mu-receptors.
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Pharmacodynamic Ceiling: Respiratory depression maximal 15-30 min, euphoria peak correlates 6-MAM.
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Tolerance Profile: Receptor desensitization onset 4-6 hours, withdrawal peaks 8-12 hours.
Distinguishes from morphine by pharmacokinetic amplification ideal for rapid tolerance studies.
Customer Research Insights
Institutional opioid researchers validate:
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“Pharmaceutical-grade heroin powder perfected our 6-MAM metabolic cascade research.” – Dr. Z., NIDA Neuropharmacology
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“Schedule I compliance exemplary; impurity profile ideal for LC-HRAM-MS validation.” – Prof. AA., Forensic Toxicology Consortium
DEA-licensed institutional feedback confirms analytical excellence.
Frequently Asked Questions
Purity analytical certification?
≥99% with 6-MAM/morphine impurities quantified <0.1%.
Schedule I possession requirements?
DEA registration + protocol approval mandatory.
Method validation suitability?
SWGDRUG/NIST Category 1 reference standard compliant.
Authorized recipient verification process?
Pre-shipment DEA registrant confirmation required.
Conduct definitive opioid research with heroin powder from Research Stimulants. Schedule I excellence for licensed institutions only.
| Quantity |
15g ,25g ,50g ,100g ,250g ,500g ,1KG |
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