Buy 5-MeO-DMT Powder | Research Stimulants

Product Description

Introduction to 5-MeO-DMT Powder: A Potent Research Tryptamine

At Research Stimulants, we are committed to providing researchers, pharmacologists, and academic institutions with top-quality research chemicals. Our 5-MeO-DMT powder (5-methoxy-N,N-dimethyltryptamine), a naturally occurring and synthetically produced tryptamine, is a key compound in our psychedelic and serotonergic portfolio. Known for its exceptional potency as a serotonin receptor agonist, 5 MeO DMT is widely utilized in neuropharmacological, behavioral, and therapeutic mechanism studies.

Researchers seeking to buy 5-MeO-DMT powder will find our premium-grade product offers ≥98% purity, verified through third-party HPLC and NMR analysis. This fine white to off-white crystalline powder is ideal for precise dosing in in vitro and in vivo experiments, delivering consistent and reproducible results. As an atypical psychedelic tryptamine, 5 MeO DMT stands out for its strong selectivity toward 5-HT1A receptors, distinguishing it from classic psychedelics like DMT or psilocybin.

Important Disclaimer: All products sold by Research Stimulants, including 5-MeO-DMT powder, are intended exclusively for laboratory and scientific research. They are not for human consumption, veterinary use, or therapeutic applications. Handling is restricted to qualified professionals due to potential risks.

What is 5-MeO-DMT? 

5-MeO-DMT, chemically 5-methoxy-N,N-dimethyltryptamine, is a substituted tryptamine alkaloid found in various plants (e.g., Virola species) and the venom of the Colorado River toad (Incilius alvarius). Its molecular formula is C13H18N2O, with a molecular weight of 218.30 g/mol. First synthesized in 1936, it has become a focal point in modern psychedelic research due to its unique pharmacological profile.

As a non-selective serotonin receptor agonist, 5-MeO-DMT exhibits highest affinity for the 5-HT1A receptor (Ki ~1.9–3 nM), with 300–1000-fold selectivity over 5-HT2A (Ki ~907 nM). This contrasts with most serotonergic psychedelics, where 5-HT2A activation predominates. It also interacts with other serotonin subtypes (5-HT2B, 5-HT2C), melatonin receptors, and potentially the serotonin transporter (SERT). Metabolized primarily by MAO-A to bufotenine (an active 5-HT2A-preferring metabolite), its effects can be modulated by MAO inhibitors.

In research settings, 5 MeO DMT powder is valued for inducing rapid-onset, short-duration mystical experiences in models, often described as intense and non-visual compared to DMT. Our product undergoes rigorous testing, with each batch accompanied by a Certificate of Analysis (COA) confirming purity and identity.

Chemical Properties and Structure Overview

5-MeO-DMT features an indole ring with a 5-methoxy substitution and an N,N-dimethyl ethylamine side chain, enhancing lipophilicity (log P ~3.30) for CNS penetration. It appears as a fine crystalline powder, soluble in organic solvents (e.g., ethanol, DMSO) but sparingly in water (freebase form).

Key properties include:

• Melting point: ~70–73°C
• Appearance: White to off-white powder
• Stability: Store in airtight, cool, dark conditions; stable for 12–24 months

Synthesis typically involves Fischer indole methods from suitable precursors, yielding high-purity material. The freebase form is common for research, though salts (e.g., succinate, fumarate) are explored for improved solubility. Our powder is supplied as freebase unless specified, optimized for lab handling.

For searches like “5-MeO-DMT chemical properties” or “tryptamine research powder,” Research Stimulants offers detailed specs, SDS, and analytical data.

Research Applications of 5-MeO-DMT Powder

5-MeO-DMT powder excels in studies of serotonergic psychedelics, particularly 5-HT1A-mediated effects on mood, anxiety, and neuroplasticity. Its rapid action and mystical profile make it ideal for modeling peak experiences and therapeutic potential.

Key applications:

• Receptor binding and functional assays (high 5-HT1A selectivity)
• Behavioral models of mystical states, ego dissolution, and antidepressant effects
• Neurogenesis and neuroprotection studies (e.g., increased cell proliferation in dentate gyrus)
• Comparative pharmacology with DMT, psilocybin, or analogs to explore receptor contributions
• Forensic reference for NPS detection

Recent investigations (up to 2026) highlight its promise in treatment-resistant depression models, with phase studies showing rapid remission via vaporized dosing. Preclinical data suggest immunomodulatory, anti-inflammatory, and pro-neuroplastic effects via 5-HT1A/2A and sigma-1 receptor pathways.

The powder format supports accurate weighing for low-dose experiments, complementing related tryptamines in our catalog.

Safety, Handling, and Legal Considerations

Handle 5 MeO DMT powder with utmost care: Use PPE, fume hoods, and avoid inhalation/ingestion. Potential hazards include intense autonomic effects (e.g., hyperthermia, hypertension) if mishandled.

Dispose per hazardous waste guidelines. Seek medical aid immediately for exposure.

Legally, 5 MeO DMT is a Schedule I controlled substance in the US (since 2011) under the Controlled Substances Act, with similar restrictions internationally (UN Schedule I analog in many jurisdictions). It is prohibited in the UK (Class A), Australia (S9), and others. Research Stimulants supplies only to verified researchers/institutions with proper licensing, complying fully with regulations. No shipments to restricted areas.

Why Choose Research Stimulants for 5 MeO DMT Powder?

We differentiate through:

• ≥98% purity, third-party verified with COA
• Discreet, tracked global shipping
• Competitive pricing and bulk options
• Expert support, SDS, and research resources

Researchers note: “The 5-MeO-DMT powder from Research Stimulants delivers exceptional consistency for our receptor studies,” – Dr. S. T., neuropharmacologist.

Explore related items: DMT Analogs, Psychedelic Safety Guide.

Frequently Asked Questions (FAQs) About 5-MeO-DMT Powder

What purity is your 5-MeO-DMT powder? ≥98%, lab-verified with COA.

How does 5-MeO-DMT differ from DMT? Higher 5-HT1A selectivity, more intense/non-visual effects, shorter duration.

Storage for 5 MeO DMT powder? Cool, dry, dark, airtight container.

Is 5-MeO-DMT for non-research use? No – strictly laboratory research; orders verified.

Payment and shipping? Secure options; fast discreet delivery.

Samples? Limited for qualified researchers – contact us.

Unlock insights into serotonergic psychedelics with premium 5-MeO-DMT powder from Research Stimulants. Optimized for keywords like “buy 5-MeO-DMT powder online,” “5 MeO DMT research chemical,” and “tryptamine psychedelic powder.” Order today!